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You are here: Home / Genitourinary / S2 E096 Infectious Disorders of the Urinary Tract

S2 E096 Infectious Disorders of the Urinary Tract

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Urinary Tract Infection

Risk Factors

  • Females are more prone than males
  • Diabetes
  • Obesity
  • Sexual Activity

Clinical Presentation

  • Burning with urination
  • Frequency
  • May present with strangely in elderly

Diagnosis

  • Symptoms alone may be enough
  • U/A
  • Cultures

Treatment

  • – Several different options for antibiotic treatment
    • Cephalexin (Keflex)
    • Fluoroquinolones
    • Bactrim is becoming less effective due to resistant organisms

Urethritis

Causes

  • Neisseria gonorrhoeae
  • Chlamydia

Clinical Presentation

  • Purulent urethral discharge (think Neisseria)
  • Clear discharge (think Chlamydia)
  • Painful voiding
  • Frequency

Labs, Studies and Physical Exam Findings

  • Urethral swab

Treatment

  • Antibiotics
    • Ceftriaxone
    • Azithromycin
    • Doxycycline

Cystitis

  • Cystitis in men is a sign of other pathology
  • Use catheters sparingly and for as short a time as possible

Causes

  • E Coli is the #1 cause
  • Enterococci

Clinical Presentation

  • It hurts when I pee! (dysuria)
  • Frequency
  • Urgency
  • Hematuria is possible

Labs, Studies and Physical Exam Findings

  • Urinalysis and culture

Treatment

  • Several different options for antibiotic treatment
    • Cephalexin (Keflex)
    • Fluoroquinolones
    • Bactrim is becoming less effective due to resistant organisms

Pyelonephritis

  • An ascending urinary tract infection

Causes

  • E. Coli is the most common cause

Clinical Presentation

  • Fever
  • Radiating flank pain
  • Dysuria
  • Abdominal pain
  • Nausea and vomiting

Labs, Studies and Physical Exam Findings

  • Costovertebral tenderness
  • U/A
    • Pyuria
    • White cell casts
  • Urine culture
  • X-ray of the kidney, ureter and bladder (KUB)
  • U/S
  • CT if necessary

Treatment

  • Antibiotics based on urine culture
    • Fluoroquinolones
    • Cephalosporins
    • Aminoglycoside
    • Bactrim

Epididymitis

  • The most frequent cause of acute pain in the scrotum
  • Associated with urethritis

Causes

  • Chlamydia trachomatis
  • Neisseria gonorrhoeae
  • Gram negative rods

Clinical Presentation

  • My scrotum hurts
  • Swollen scrotum
  • Urethral discharge
  • Pain with voiding
  • Fever

Labs, Studies and Physical Exam Findings

  • Prehn’s sign is positive –  elevating the scrotum provides pain relief
  • CBC
  • Gram stain and culture of discharge
    • Gram negative intracellular diplococci = N. gonorrhoeae
    • No visible organism but lots of WBCs = Chlamydia
  • Urine culture
  • U/A

Treatment

  • Antibiotics which cover N. gonorrhoeae and Chlamydia
    • Treat sexual partners as well
    • Macrolides – Azithromycin
    • Cephalosporins – Cefixime

Orchitis

Causes

  • Chlamydia
  • Gonorrhea
  • Mumps

Clinical Presentation

  • Severe scrotal pain
  • Scrotal swelling
  • Hematuria

Labs, Studies and Physical Exam Findings

  • U/A
  • Urine culture

Treatment

  • Scrotal elevation and ice
  • NSAIDS
  • Opiates

Prostatitis Acute & Chronic

Causes

  • Acute
    • E. coli
    • Pseudomonas
  • Chronic
    • Gram negative rods
    • Enterococcus

Clinical Presentation

  • Acute
    • Fever
    • Pain with voiding
    • Perineal pain
  • Chronic

Labs, Studies and Physical Exam Findings

  • U/A
  • Urine culture will be  positive
  • Acute
    • Tenderness with rectal exam
  • Chronic
    • Rectal exam may be normal or have a boggy prostate

Treatment

  • Acute patient may require hospitalization
    • IV antibiotics
    • Catheterization may be necessary
  • Trimethoprim – sulfamethoxazole (Bactrim) for 6-12 weeks
  • Fluoroquinolones for 6-12 weeks
  • Cephalexin 6-12 weeks
  • Erythromycin 6-12 weeks
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