Sickle Cell Anemia Genetic Pattern Autosomal recessiveHomozygote inheritance of Hemoglobin S (HbS)Predominantly seen in the African American populationOxygenated HbS does not dissolve well and forms a gel that distorts the shape of the RBC into a sickle. This makes the cells "sticky" and less … [Read more...]

Macrocytic Anemia Macrocytic anemias produce strange dysfunctional blood cells. This will result in some hemolysis and progress to splenic dysfunction as the spleen becomes overloaded.Howell-Jolly bodies are DNA remnants seen with a macrocytic anemia or a damaged spleen. You will find them in B12 … [Read more...]

Anemia Anemia means low RBC or Hgb count. A patient could be bleeding out and have a low Hgb or they could have a dietary deficiency. Anemia is a starting place. As we get more detailed and more specific we can get a more clear diagnosis and treatment plan. One of the easiest places to start … [Read more...]

Red Blood Cells Priming Questions What are the four polypeptide chains that make up hemoglobin? Define polycythemia What does MCV stand for and what does it mean? Define hemolysis. Red Blood Cells Simplified The specific shape of a RBC gives it an increased surface area … [Read more...]