Hypercoagulable states (Thrombophilia) Where is the problem?Clotting FactorsToo manyToo activePlateletsToo manyToo activeVascular injurySurgeryTraumaStasisVirchow’s triadStasisHypercoagulable stateVascular injuryGerman doctor and scientist who first described the mechanism for a pulmonary … [Read more...]
S2 E081 Coagulation Disorders
Coagulation Factor Disorders von Willebrand Disease A spectrum of low production to production of poorly functioning von Willebrand’s Factor. von Willebrand’s factor (vWF) has two major functions. vWF helps platelets to stick together in the subendothelial collagenvWF binds to and maintains … [Read more...]
S2 E080 Clotting overview
Our two main players in coagulation are platelets and clotting factors. To help make things clear we can split up these two agents into separate categories even though the work in concert. Primary hemostasis When a blood vessel is damaged, the subendothelium spaces are exposed to … [Read more...]
S2 E079 Lymphoma and an important tactic for the PANCE
Lymphoma A group of malignancies that develop from lymphocytesThere are over 80 types of lymphoma.Unlike leukemia lymphoma is a solid tumorGenerally speaking (this is by no means 100% true)lymphoma develops in the lymphatic systemThink lymph nodes and spleenLeukemia develops in the bone marrowThe … [Read more...]
S2 E078 Leukemia
Leukemia Leukemia is a disease characterized by the overproduction of a particular type of blood cell. This process often inhibits the production of normal blood cells These leukemia cells do not function as proper cells Leukemia does not form a solid tumor. Rather it produces blood cells … [Read more...]